Of Notice is that, because of PEA’s superior lipophilicity, micronized or ultra-micronized formulations are considered being additional conveniently absorbable, with additional favorable pharmacokinetics and larger efficacy. Whilst There exists some evidence supporting this principle, there is still no proof from the superiority of micronized PEA
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2005). These benefits weren't stunning if we consider that PEA is really a poorly water?soluble compound, which might Restrict its oral absorption and bioavailability, Nonetheless they might also suggest a short?lived action of PEA, in arrangement with the fact that this compound is degraded by two distinctive hydrolases, which is, NAAA and FAAH. L
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